BioMedical Admissions Test (BMAT) 2025 – 400 Free Practice Questions to Pass the Exam

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What type of genetic inheritance pattern is associated with Cystic Fibrosis?

Dominant

Recessive

Cystic Fibrosis is associated with a recessive genetic inheritance pattern. This means that an individual must inherit two copies of the mutated CFTR gene, one from each parent, to express the disease. If a person has only one copy of the mutated gene, they are a carrier but typically do not show symptoms of the disease. This characteristic of requiring two copies for the phenotype to manifest is a key feature of recessive inheritance.

In contrast, dominant inheritance would result in individuals expressing the trait even when only one copy of the mutated gene is present, while X-linked inheritance involves genes located on the X chromosome, typically affecting males more severely due to their single X chromosome. Incomplete dominance is a situation where the phenotype is an intermediate blend of the traits from both parents, which is not applicable in the case of Cystic Fibrosis. Thus, the pattern of inheritance that best describes Cystic Fibrosis is indeed recessive.

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X-linked

Incomplete dominance

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